Free software for macOS

Audacity

Multimedia

Multi-track audio recorder and editor

Desktop utility that repeats mouse clicks on a schedule you define

Blender

Design

3D creation suite covering modelling, animation, rendering and video editing

Keeps a DNS record pointed at a connection whose IP address keeps changing

Desktop client for browsing, editing and watching etcd clusters

GIMP

Design

Raster image editor for retouching, composition and drawing

HandBrake

Multimedia

Video transcoder that converts almost any source to MP4, MKV or WebM

Inkscape

Design

Vector graphics editor that works natively in SVG

Kdenlive

Multimedia

Multi-track video editor built on the MLT framework

Krita

Design

Digital painting application built around its brush engines

LibreOffice

Productivity

Office suite with word processor, spreadsheet, presentation and database tools

OBS Studio

Multimedia

Screen recording and live streaming with a scene and source compositor

Shotcut

Multimedia

Video editor with a timeline, filters and a portable Windows build

Thunderbird

Productivity

Desktop email client with calendar, contacts and feed reading

VLC media player

Multimedia

Media player that opens almost any audio or video file without extra codecs

Screen capture tool with an annotation editor and a local capture history