Coot

Coot is a software application for macromolecular model building, specifically tailored for crystallographic research. It provides tools for the visualization and manipulation of atomic models, allowing researchers to fit molecular structures into electron density maps. The software supports the manual adjustment of coordinates, enabling the refinement of protein and nucleic acid structures based on experimental data.

Designed for the Linux environment, Coot integrates with various crystallographic software suites to facilitate the structural biology workflow. It includes features for real-time map updating and geometric validation during the model building process. The application is distributed under a combination of GPL and LGPL licenses, reflecting its development history within the scientific community.